|rosuvastatin vs pravastatin muscle pain||1.24||0.4||9789||82|
Crestor (rosuvastatin) is one of the most effective statins to improve cholesterol. It's also available as a generic. Pravachol (pravastatin) can improve cholesterol, but it's not as strong as other statin medicines. It does cause fewer side effects and is safer for your kidneys and liver.Is rosuvastatin more dangerous than other statins?
The results showed that the relative risk rates were consistently higher for rosuvastatin than for the other statins. Compared with rosuvastatin, the risk of muscle-related adverse effects was 74% as high for fluvastatin, 55% as high for atorvastatin, 26% as high for simvastatin, 17% as high for pravastatin, and 7.5% as high for lovastatin.Is pravastatin lipophilic or hydrophilic?
Hydrophilic statins (pravastatin, rosuvastatin) may cause less muscular events than lipophilic statins (e.g. simvastatin, atorvastatin) due to lower passive diffusion into muscle cells.” The statin users were divided into groups: New patient group 1: pravastatin 20-40 mg (hydrophilic) vs simvastatin 10-20 mg (lipophilic).How effective are rosuvastatin and pravastatin at reducing LDL-C?
Results: At 12 weeks, percent LDL-C reductions after both 5-mg and 10-mg rosuvastatin treatment, which were 39.1% and 47.4%, respectively, were significantly different (P <.05) from LDL-C reductions after 20-mg pravastatin (26.5%) and 20-mg simvastatin (34.6%) treatment.