Keyword Analysis & Research: torvaptan
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Tolvaptan Uses, Side Effects & Warnings - Drugs.com
Mar 09, 2021 · Tolvaptan dosing information. Usual Adult Dose for Hyponatremia: Initial dose: 15 mg orally once a day Maintenance dose: Increase the dose to 30 mg once a day, after at least 24 hours, to a maximum …
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Tolvaptan - Wikipedia
Tolvaptan, sold under the brand name Samsca among others, is an aquaretic drug that functions as a selective, competitive vasopressin receptor 2 (V2) antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH). Tolvaptan was approved by the U.S. Food and Drug Administration (FDA) on May 19, 2009, and is sold by Otsuka Ph…
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Tolvaptan | PKD Foundation
Tolvaptan is a medication (taken twice a day as an oral pill) that affects how the kidneys control the concentration of urine. It has been shown to slow down the growth of kidney cysts (total kidney volume) when …
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When did tolvaptan get an orphan drug designation?
The U.S. Food and Drug Administration (FDA) granted tolvaptan a fast track designation for clinical trials investigating its use for the treatment of polycystic kidney disease. The FDA granted Jynarque an orphan drug designation in April 2012, for the treatment of autosomal dominant polycystic kidney disease.
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What do you need to know about tolvaptan tablets?
This monograph only gives information about tolvaptan tablets (Samsca) to treat low levels of sodium in the blood. If you are using this medication to slow the worsening of your kidney function, read the monograph entitled tolvaptan (kidney disease).
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Who is the manufacturer of tolvaptan in India?
Tolvaptan. Tolvaptan was approved by the U.S. Food and Drug Administration (FDA) on May 19, 2009, and is sold by Otsuka Pharmaceutical Co. under the trade name Samsca and in India is manufactured & sold by MSN laboratories Ltd. under the trade name Tolsama & Tolvat .
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What are the secondary end points of tolvaptan?
Sequential secondary end points included a composite of time to clinical progression (defined as worsening kidney function, kidney pain, hypertension, and albuminuria) and rate of kidney-function decline.
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