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BRCA gene test for breast and ovarian cancer risk - Mayo Clinic
https://www.mayoclinic.org/tests-procedures/brca-gene-test/about/pac-20384815
WebOct 21, 2023 · Negative or uncertain test result. A negative test result means that no gene changes were found. However, you could still have a higher risk of cancer. A negative result is considered a "true negative" only if it finds that you don't carry the specific gene change that runs in your family.
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BRCA Gene Mutations: Cancer Risk and Genetic Testing
https://www.cancer.gov/about-cancer/causes-prevention/genetics/brca-fact-sheet
WebIf a close blood relative of the tested person is known to carry a harmful BRCA1 or BRCA2 variant, a negative test result is clear: it means the tested person did not inherit the harmful variant that is present in the family and cannot pass it to their children. A person with such a test result, called a true negative, has a risk of cancer that ...
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BRCA Testing for Breast & Ovarian Cancer Risk: Procedure
https://my.clevelandclinic.org/health/diagnostics/22728-brca-testing
WebWhat does it mean if the results are negative? A negative result means you don’t have a BRCA mutation. It also means your children won’t inherit a BRCA mutation from you. A negative BRCA test doesn’t guarantee you won’t get cancer. It means your risk is likely the same as the general population.
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Understanding Your Genetic Test Results - Susan G. Komen®
https://www.komen.org/breast-cancer/risk-factor/gene-mutations-genetic-testing/understanding-your-genetic-test-results/
Web6 days ago · Genetic test results show if you have a BRCA1, BRCA2 (BRCA1/2) or other inherited gene mutation related to breast cancer. For some people with breast cancer, test results help guide treatment. There are 3 possible results: Benign or likely benign variant (the test is negative, meaning the results are normal). The test shows normal findings …
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Inherited Cancer Risk: BRCA Mutation | Johns Hopkins Medicine
https://www.hopkinsmedicine.org/health/conditions-and-diseases/breast-cancer/inherited-cancer-risk-brca-mutation
WebInheriting damaged copies of the BRCA1 or BRCA2 genes can increase the risk for breast cancer and ovarian cancer in women and the risk for breast and prostate cancer in men, as well as other cancers. Here is what you need to know about genetic factors in breast cancer, who may be at risk and how people with BRCA mutations can work with their ...
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BRCA1 and BRCA2: Cancer Risks and Management (PDQ®)
https://www.ncbi.nlm.nih.gov/books/NBK589498/
WebMar 3, 2023 · Genetics. Germline pathogenic variants in BRCA1/BRCA2 are associated with ovarian cancer, fallopian tube cancer, primary peritoneal cancer, male breast cancer, prostate cancer, pancreatic cancer, and early-onset breast cancer. BRCA1/BRCA2 -associated cancer risks are inherited in an autosomal dominant manner.
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BRCA Gene Mutations & Breast Cancer Risk
https://www.breastcancer.org/genetic-testing/brca
WebGenetic Testing for Breast Cancer. How BRCA and Other Gene Mutations Work. Healthy BRCA1 and BRCA2 genes prevent breast cancer and certain other cancers from developing. But mutations in these genes can lead to cancer. Reviewed by 1 medical adviser. Sections. How BRCA gene mutations affect cancer risk. Inherited BRCA gene …
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Genetic Testing for Hereditary Breast and Ovarian Cancer | CDC
https://www.cdc.gov/genomics/disease/breast_ovarian_cancer/testing.htm
WebIf you have a negative test result, the test didn’t find a mutation. However, what this means for you depends on whether you have already had breast or ovarian cancer and whether another relative is known to have a mutation. If you …
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BRCA Genetic Test - Understand the Test & Your Results - MSD …
https://www.msdmanuals.com/-/media/Manual/LabTests/BRCAGeneticTest.html
WebMost results are described as negative, uncertain, or positive, and typically mean the following: A negative result means no BRCA gene mutation was found, but it doesn't mean you won't ever get cancer. An uncertain result means some kind of BRCA gene mutation was found, but it may or may not be linked with an increased cancer risk. You may need ...
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BRCA Genetic Test: MedlinePlus Medical Test
https://medlineplus.gov/lab-tests/brca-test/
WebWhat is it used for? This test is used to find out if you have harmful changes in your BRCA1 or BRCA2 genes that increase your risk of getting certain cancers, especially breast, ovarian, prostate, and pancreatic cancer. Why do I need a BRCA gene test? Harmful BRCA gene variants are rare. They affect only about 0.2 percent of the U.S. population.
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