Keyword Analysis & Research: ertapenem enterococci
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Properties and potential of ertapenem | Journal of ...
Pneumococci, streptococci and enterococci. Ertapenem has good anti-pneumococcal activity although, as with all β-lactams, sensitivity is reduced for penicillin-non-susceptible isolates (Figure 2). 10, 11 In general, MICs are equal to or two-fold below those of benzylpenicillin, but two- to four-fold above those of meropenem and imipenem.
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Carbapenems - Infectious Diseases - Merck Manuals ...
Most Enterococcus faecalis and many Pseudomonas aeruginosa strains, including those resistant to broad-spectrum penicillins and cephalosporins, are susceptible to imipenem, meropenem, and doripenem but are resistant to ertapenem. However, meropenem and doripenem are less active against E. faecalis than imipenem.
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Role of Ertapenem for the Treatment of Complicated Intra ...
Enterococcus faecalis is isolated in up to 30% of intra-abdominal infections (IAIs) .However, its pathogenicity in mixed infections remains unclear. Ertapenem is a broad-spectrum antibiotic with activity against a range of gram-positive, gram-negative, and anaerobic gastrointestinal organisms but with limited activity against E. faecalis [4, 5]. ...
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Ertapenem 1g Powder for Concentrate for Solution for ...
Average plasma concentrations of ertapenem following a single 30 minute intravenous infusion of a 1 g dose in three patients 13 to 17 years of age were 155.9 micrograms/mL (C max) at 0.5 hour postdose (end of infusion), and 6.2 micrograms/mL at 12 hour postdose. Distribution. Ertapenem is highly bound to human plasma proteins.
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Ertapenem - IDStewardship
KEY POINTS Ertapenem (Invanz) is a carbapenem and beta-lactam antibiotic that interferes with bacterial cell wall synthesis in susceptible pathogens Reserve use whenever possible, as it is one of our last-line antibiotics Has activity against ESBL+ E. coli, Klebsiella and other multi-drug resistant Gram negative pathogens Does NOT have activity versus Acinetobacter, Pseudomonas or Enterococcus ...
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Enterococcal Infections - Infectious Diseases - Merck ...
Enterococci are gram-positive, facultative anaerobic organisms. Enterococcus faecalis and E. faecium cause a variety of infections, including endocarditis, urinary tract infections, prostatitis, intra-abdominal infection, cellulitis, and wound infection as well as concurrent bacteremia.
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Gram positive bacteria - Enterococcus - Infectious Disease ...
Gram positive bacteria – Enterococcus What are Gram positive bacteria – enterococci? Enterococci are ubiquitous gram-positive cocci, calatase-negative, non-spore-forming, facultative anaerobic organisms, that belong to the Lancefield group D streptococci. Enterococci are normally present, as colonizers, in the intestinal tract of human beings and animals, and can be recovered from feces in ...
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Activity of Moxifloxacin, Imipenem, and Ertapenem against ...
In comparison to ertapenem, which exerts no activity against enterococci, moxifloxacin is variably active against E. faecalis. Furthermore, moxifloxacin was found to affect viable counts of the pathogens in mixed cultures more effectively and more rapidly than the two carbapenems. Thus, moxifloxacin may be superior to imipenem and ertapenem and ...
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In Vitro Activity of Ertapenem: Review of Recent Studies
Ertapenem is a long-acting, 1beta-methyl parenteral Group 1 carbapenem antibiotic that has a broad antibacterial spectrum and once-a-day dosing supported by clinical studies. Ertapenem is active against both Gram-positive and Gram-negative bacteria, including Enterobacteriaceae, Streptococcus pneumo …
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