In Cushing syndrome, the level of corticosteroids is excessive, usually due to taking corticosteroid drugs or overproduction by the adrenal glands.What are the signs and symptoms of pediatric Cushing's disease?
Diagnosis and treatment of pediatric Cushing's disease. The most common symptom of paediatric Cushing's syndrome is weight gain, but a unique feature is the effect on linear growth; the combination of weight gain and decreased height velocity is pathognomonic for paediatric Cushing's syndrome.Can too much pituitary stimulation cause Cushing syndrome?
If Cushing syndrome is caused by too much pituitary stimulation (Cushing disease), the blood level of cortisol will fall to some extent, although not as much as in people who do not have Cushing syndrome. A high ACTH level further suggests overstimulation of the adrenal gland by the pituitary.What is mifepristone in Cushing's syndrome?
Mifepristone is a glucocorticoid and progesterone receptor antagonist that can ameliorate the signs and symptoms of Cushing's syndrome. Merits and pitfalls of mifepristone in Cushing's syndrome. Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome.