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NDNF interneurons, Spartans of the cortical column: Small in …
https://www.cell.com/neuron/fulltext/S0896-6273(21)00463-3
WEB, in this issue of Neuron, attack L1 NDNF INs with thoroughness and rigor.Focusing on primary visual cortex (V1), the authors use a combination of two-photon imaging, in vivo and in vitro patch-clamp electrophysiology, optogenetics, pharmacology, and retrograde monosynaptic tracing to characterize NDNF INs. First, the authors show that V1 NDNF …
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Intrathecal delivery of AAV-NDNF ameliorates disease ... - PubMed
https://pubmed.ncbi.nlm.nih.gov/37766430/
WEBNov 1, 2023 · Here we show a marked effect of AAV-mediated over-expression of neuron-derived neurotrophic factor (NDNF) on SOD1 G93A ALS model mice. First, we adopt AAV-PHP.eB capsid to enable widespread expression of target proteins in the brain and spinal cord when delivered intrathecally. Then we tested the effects of AAV-NDNF on SOD1 …
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Intrathecal delivery of AAV-NDNF ameliorates disease
https://www.sciencedirect.com/science/article/pii/S1525001623005051
WEBNov 1, 2023 · AAV vectors have the advantage of conferring sustained expression of target genes in transduced cells after a single treatment. We determined behavior consequences after AAV-NDNF or control virus (5 × 10 11 vg per mouse) administration at different stages of disease in the SOD1 G93A mice. First, we intrathecally injected viruses into SOD1 …
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NDNF interneurons in layer 1 gain-modulate whole cortical …
https://www.cell.com/neuron/fulltext/S0896-6273(21)00327-5
WEBMay 25, 2021 · Cohen-Kashi Malina et al. show that visual cortex L1 NDNF INs are strongly driven by arousal. Active NDNF INs are evenly spread in L1 and gain-modulate local excitatory neurons in all cortical layers during high-arousal states by directly inhibiting their apical dendrites while disinhibiting their somata via Parvalbumin-expressing interneurons.
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Defeat - Friday Night Funkin' [FULL SONG] (1 HOUR) - YouTube
https://www.youtube.com/watch?v=Un2-0aByci0
WEBDefeat - Friday Night Funkin' [FULL SONG] (1 HOUR)Defeat - Friday Night Funkin' VS Impostor OST by Rareblinhttps://www.youtube.com/watch?v=s6rpdFINCXAVS Impo...
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Stratum Lacunosum-moleculare Interneurons of the …
https://www.biorxiv.org/content/10.1101/2021.06.11.448103v1
WEBJun 12, 2021 · Encoding and retrieval of memory are two processes serving distinct biological purposes but operating in highly overlapping brain circuits. It is unclear how the two processes are coordinated in the same brain regions, especially in the hippocampal CA1 region where the two processes converge at the cellular level. Here we find that the …
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NDNF interneurons in layer 1 gain-modulate whole cortical columns
https://www.sciencedirect.com/science/article/pii/S0896627321003275
WEBJul 7, 2021 · Next, we assessed the visual response properties of L1 NDNF INs in the mouse V1 and compared them with those of somatostatin-expressing INs (SST INs), an IN subtype that also specializes in targeting the apical dendrites of local excitatory neurons (Tremblay et al., 2016), and with those of excitatory neurons in L2/3 of the cortex.To this …
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How to Change Your Keybinds in Friday Night Funkin' Using ... - YouTube
https://www.youtube.com/watch?v=wgL6Ofow5yk
WEBMay 10, 2021 · Do you want to customize your controls in Friday Night Funkin', the popular rhythm game? Watch this video to learn how to use AutoHotKey to change your keybinds easily and quickly. You will also ...
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Neuron-derived neurotrophic factor functions as a novel ... - PubMed
https://pubmed.ncbi.nlm.nih.gov/24706764/
WEBMay 16, 2014 · Strategies to stimulate revascularization are valuable for cardiovascular diseases. Here we identify neuron-derived neurotrophic factor (NDNF)/epidermacan as a secreted molecule that is up-regulated in endothelial cells in ischemic limbs of mice. NDNF was secreted from cultured human endothelial cel …
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Welcome to python-ndn’s documentation! — python-ndn 0.0.0 …
https://python-ndn.readthedocs.io/en/latest/index.html
WEBWelcome to python-ndn’s documentation! Table Of Contents . python-ndn; Installation. Instructions for developer; ndn.app package. Introduction; Keyword Arguments
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