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Luspatercept Uses, Side Effects & Warnings - Drugs.com
https://www.drugs.com/mtm/luspatercept.html
Luspatercept is for use in adults with a blood disorder called beta thalassemia, in which the body does not produce enough hemoglobin (HEEM o glo bin). Hemoglobin carries oxygen through your blood to tissues and organs. Luspatercept is used to treat anemia (lack of red blood cells) in adults with beta … See more
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Luspatercept - StatPearls - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK560635/
Web ResultJul 10, 2023 · Luspatercept is a fusion protein consisting of the extracellular domain of activin receptor type IIB fusion protein and … Affiliations: Kern Medical Center
Affiliations: Kern Medical Center
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Luspatercept-aamt - NCI - National Cancer Institute
https://www.cancer.gov/about-cancer/treatment/drugs/luspatercept-aamt
Web ResultLuspatercept-aamt is approved to treat: Anemia caused by certain types of myelodysplastic syndromes or myelodysplastic/ myeloproliferative neoplasms. It …
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FDA approves luspatercept-aamt for anemia in adults with MDS
https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-luspatercept-aamt-anemia-adults-mds
Web ResultOn April 3, 2020, the Food and Drug Administration approved luspatercept-aamt (REBLOZYL, Celgene Corporation) for the treatment of anemia failing an …
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Luspatercept: Uses, Interactions, Mechanism of Action
https://go.drugbank.com/drugs/DB12281
Web ResultOct 20, 2016 · Luspatercept is a recombinant fusion protein comprised of a modified extracellular domain of activin receptor type IIB fused to the FC domain of human …
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Long-Term Efficacy and Safety of Luspatercept for …
https://ascopubs.org/doi/10.1200/JCO.21.02476
Web ResultAug 23, 2022 · Luspatercept (ACE-536), a first-in-class erythroid-maturation agent, binds transforming growth factor-β superfamily ligands, diminishing Smad2/3 signaling and enhancing late-stage …
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Luspatercept-aamt Injection: MedlinePlus Drug Information
https://medlineplus.gov/druginfo/meds/a620043.html
Web ResultLuspatercept-aamt is in a class of medications called erythroid maturation agents. It works by increasing the number and quality of red blood cells. How should this …
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Luspatercept - Wikipedia
https://en.wikipedia.org/wiki/Luspatercept
Web ResultLuspatercept, sold under the brand name Reblozyl, is a medication used for the treatment of anemia in beta thalassemia and myelodysplastic syndromes. [4] The …
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Luspatercept in Patients with Lower-Risk …
https://www.nejm.org/doi/full/10.1056/NEJMoa1908892
Web ResultLuspatercept reduced the severity of anemia in patients with lower-risk myelodysplastic syndromes with ring sideroblasts who had been receiving regular red-cell transfusions and who had disease...
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A Phase 3 Trial of Luspatercept in Patients with …
https://www.nejm.org/doi/full/10.1056/NEJMoa1910182
Web ResultLuspatercept, a recombinant fusion protein that binds to select transforming growth factor β superfamily ligands, may enhance erythroid maturation and reduce the transfusion burden (the total...
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