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enhancer | Learn Science at Scitable - Nature
https://www.nature.com/scitable/definition/enhancer-163/
WEBenhancer. Enhancer sequences are regulatory DNA sequences that, when bound by specific proteins called transcription factors, enhance the transcription of an associated gene.
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Enhancers: five essential questions | Nature Reviews Genetics
https://www.nature.com/articles/nrg3458
WEBMar 18, 2013 · Five prominent researchers discuss some of the key outstanding questions in enhancer biology. It is estimated that the human genome contains hundreds of thousands of enhancers, so understanding...
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Enhancer (genetics) - Wikipedia
https://en.wikipedia.org/wiki/Enhancer_(genetics)
WEBIn genetics, an enhancer is a short (50–1500 bp) region of DNA that can be bound by proteins to increase the likelihood that transcription of a particular gene will occur. These proteins are usually referred to as transcription factors. Enhancers are cis-acting. They can be located up to 1 Mbp (1,000,000 bp) away from the gene, upstream or ...
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Transcriptional enhancers: from properties to genome-wide
https://www.nature.com/articles/nrg3682
WEBMar 11, 2014 · This paper reports the first sequence that can increase transcription levels from a given promoter, defines the term enhancer and describes many enhancer properties.
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Mechanisms of enhancer action: the known and the unknown
https://genomebiology.biomedcentral.com/articles/10.1186/s13059-021-02322-1
WEBApr 15, 2021 · However, our understanding of the full complement of regulatory proteins and the definitive mechanics of enhancer action is incomplete. Here, we review recent findings to present some emerging concepts on enhancer action and also outline a …
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Enhancer function: mechanistic and genome-wide insights come …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441652/
WEBJul 3, 2014 · Enhancers are cis -acting DNA regulatory elements that increase the transcriptional output of target genes to influence the destiny of cells during development and differentiation. Enhancers may reside far from their in vivo targets, raising key mechanistic questions about how they communicate with promoters.
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Enhancers, gene regulation, and genome organization - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8015720/
WEBApr 1, 2021 · They contain binding sites for lineage-regulating transcription factors and are highly cell type-specific. Typically located at long genomic distances from their target genes, enhancers may be in upstream or downstream intergenic regions, in intronic sequences, or even in introns of unrelated genes.
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Enhancer Definition & Meaning - Merriam-Webster
https://www.merriam-webster.com/dictionary/enhancer
WEBMar 31, 2024 · noun. en· hanc· er in-ˈhan (t)-sər. en-. 1. : one that enhances. 2. : a nucleotide sequence that increases the rate of genetic transcription by preferentially increasing the activity of the nearest promoter on the same DNA molecule.
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ENHANCER | definition in the Cambridge English Dictionary
https://dictionary.cambridge.org/us/dictionary/english/enhancer
WEBsomething that is used to strengthen or improve the quality of something. Enhancer is usually used as a combining form: mood enhancer Music can be a mood enhancer. flavor …
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ENHANCER | English meaning - Cambridge Dictionary
https://dictionary.cambridge.org/dictionary/english/enhancer
WEBENHANCER definition: 1. something that is used to strengthen or improve the quality of something. Enhancer is usually…. Learn more.
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