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Pharmacogenetics Guidelines: Overview and …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868558/
WEBJan 25, 2021 · First, the level of evidence for the functionality of a variant of a pharmacogene is considered and assigned to a three-level scale: demonstrated, probable, or potential functionality. Only variants with demonstrated or probable functionality are … Author: Heshu Abdullah-Koolmees, Antonius M. van Keulen, Marga Nijenhuis, Vera H. M. Deneer Publish Year: 2021
Author: Heshu Abdullah-Koolmees, Antonius M. van Keulen, Marga Nijenhuis, Vera H. M. Deneer
Publish Year: 2021
DA: 12 PA: 36 MOZ Rank: 77
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A comparison of the guidelines of the Clinical …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723247/
WEBDPWG reviews the level of evidence and the level of clinical relevance on separate scales using a five-point (0–4) and seven-point (AA-F) scale, respectively, while the CPIC rates the level of evidence on a three-point (weak-moderate-high) scale (36;37). Author: P.C.D. Bank, K.E. Caudle, J.J. Swen, R.S. Gammal, M. Whirl-Carrillo, T.E. Klein, M.V. Relling, H.J. ... DOI: 10.1002/cpt.762 Publish Year: 2018 Published: 2018/04
Author: P.C.D. Bank, K.E. Caudle, J.J. Swen, R.S. Gammal, M. Whirl-Carrillo, T.E. Klein, M.V. Relling, H.J. ...
DOI: 10.1002/cpt.762
Publish Year: 2018
Published: 2018/04
DA: 57 PA: 57 MOZ Rank: 20
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Dutch Pharmacogenetics Working Group (DPWG) …
https://www.nature.com/articles/s41431-021-01004-7
WEBNov 16, 2021 · The level of evidence was scored using a five-point scale ranging from 0 to 4, with 0 being the lowest (data on file) and 4 being the highest (published controlled studies of good quality or... Author: Jurriaan M J L Brouwer, Jurriaan M J L Brouwer, Marga Nijenhuis, Bianca Soree, Henk-Jan Guchelaar, J... Publish Year: 2021
Author: Jurriaan M J L Brouwer, Jurriaan M J L Brouwer, Marga Nijenhuis, Bianca Soree, Henk-Jan Guchelaar, J...
Publish Year: 2021
DA: 96 PA: 22 MOZ Rank: 49
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Dutch Pharmacogenetics Working Group (DPWG) …
https://www.nature.com/articles/s41431-019-0540-0
WEBNov 19, 2019 · The DPWG has concluded that four variants have sufficient evidence to be implemented into clinical care: DPYD*2A (c.1905+1G>A, IVS14+1G>A), DPYD*13 (c.1679T>G), c.2846A>T and c.1236G>A (in... Author: Carin A T C Lunenburg, Cathelijne H van der Wouden, Marga Nijenhuis, Mandy H Crommentuijn-van Rhenen... Publish Year: 2020
Author: Carin A T C Lunenburg, Cathelijne H van der Wouden, Marga Nijenhuis, Mandy H Crommentuijn-van Rhenen...
Publish Year: 2020
DA: 10 PA: 65 MOZ Rank: 18
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Pharmacogenomic information from CPIC and DPWG …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7781807/
WEBDec 11, 2020 · Bank et al. reported that CPIC and DPWG showed a high level of consistency; however, some differences between them existed such as methodology and terminology . Methodology for the scaling level of evidence, utilizing the source of information and processing establishment of dose recommendation between the … Author: Deok Yong Yoon, Soyoung Lee, Mu Seong Ban, In Jin Jang, Seunghwan Lee DOI: 10.12793/tcp.2020.28.e18 Publish Year: 2020 Published: 2020/12
Author: Deok Yong Yoon, Soyoung Lee, Mu Seong Ban, In Jin Jang, Seunghwan Lee
DOI: 10.12793/tcp.2020.28.e18
Publish Year: 2020
Published: 2020/12
DA: 47 PA: 31 MOZ Rank: 28
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Pharmacogenetics Guidelines: Overview and …
https://pubmed.ncbi.nlm.nih.gov/33568995/
WEBJan 25, 2021 · The following drugs have recommendations on genetic testing with the highest level: abacavir (HLA), clopidogrel (CYP2C19), fluoropyrimidines (DPYD), thiopurines (TPMT), irinotecan (UGT1A1), codeine (CYP2D6), and cisplatin (TPMT). The guidelines cover many drugs and genes, genotypes, or predicted phenotypes.
DA: 62 PA: 15 MOZ Rank: 76
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Dutch Pharmacogenetics Working Group (DPWG) …
https://www.nature.com/articles/s41431-021-00920-y
WEBJul 15, 2021 · DPWG guidelines are checked for agreement with current evidence every 3–5 years in general. An updated version of the guideline will be published if recommendations are altered.
DA: 91 PA: 37 MOZ Rank: 90
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(PDF) Pharmacogenetics Guidelines: Overview and …
https://www.researchgate.net/publication/348767401_Pharmacogenetics_Guidelines_Overview_and_Comparison_of_the_DPWG_CPIC_CPNDS_and_RNPGx_Guidelines
WEBJan 25, 2021 · The following drugs have recommendations on genetic testing with the highest level: abacavir (HLA), clopidogrel (CYP2C19), fluoropyrimidines (DPYD), thiopurines (TPMT), irinotecan...
DA: 38 PA: 28 MOZ Rank: 25
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Moving Pharmacogenetics into Practice: It’s All About …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376790/
WEBPharmGKB ® has clinically annotated over 160 gene-drug pairs to date with high levels of evidence. In reference to Case 1, the tamoxifen/CYP2D6 association has the highest level of evidence per CPIC (level A), DPWG (level 4), and PharmGKB ® (level 1A). The evidence on the FDA-cleared tamoxifen label is considered actionable by PharmGKB ®.
DA: 19 PA: 41 MOZ Rank: 74
