Keyword Analysis & Research: cardiolipin
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Cardiolipin - Wikipedia
https://en.wikipedia.org/wiki/Cardiolipin
WEBCardiolipin (IUPAC name 1,3-bis (sn-3’-phosphatidyl)-sn-glycerol, " sn " designating stereospecific numbering) is an important component of the inner mitochondrial membrane, where it constitutes about 20% of the total lipid composition. It can also be found in the membranes of most bacteria.
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Role of Cardiolipin in Mitochondrial Function and Dynamics in …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678812/
WEBJul 16, 2019 · Cardiolipin (CL) is a unique phospholipid which is localized and synthesized in the inner mitochondrial membrane (IMM). It is now widely accepted that CL plays a central role in many reactions and processes involved …
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Cardiolipin, the heart of mitochondrial metabolism - PubMed
https://pubmed.ncbi.nlm.nih.gov/18425414/
WEBIn the mitochondrial membrane cardiolipin plays an important role in energy metabolism, mainly by providing stability for the individual enzymes and enzyme complexes involved in energy production. Moreover, cardiolipin is involved in different stages of the mitochondrial apoptotic process and in mitochondrial membrane dynamics.
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The Role of Cardiolipin in Cardiovascular Health - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537736/
WEBAug 2, 2015 · Cardiolipin (CL), the signature phospholipid of mitochondrial membranes, is crucial for both mitochondrial function and cellular processes outside of the mitochondria. The importance of CL in cardiovascular health is underscored by the life-threatening genetic disorder Barth syndrome (BTHS), which manifests clinically as …
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Cardiolipin, the Mitochondrial Signature Lipid: Implication in Cancer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662448/
WEBOct 28, 2020 · Cardiolipins (CLs) are specific phospholipids of the mitochondria composing about 20% of the inner mitochondria membrane (IMM) phospholipid mass. Dysregulation of CL metabolism has been observed in several types of cancer.
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Cardiolipin exposure on the outer mitochondrial membrane
https://www.nature.com/articles/s41467-018-03241-9
WEBFeb 26, 2018 · Nature Communications - Cardiolipin is a phospholipid component of the inner mitochondrial membrane. Here the authors demonstrate that cardiolipin interacts with mutant α-synuclein, and that...
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Cardiolipin - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/neuroscience/cardiolipin
WEBCardiolipin is a phospholipid unique to mitochondria that is critical for the optimal activity of the ETC. Cardiolipin contains two phosphatidic acid groups linked by a glycerol with the majority of cardiolipin species containing four linoleic acid groups (C18:2).
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Role of Cardiolipin in Mitochondrial Function and Dynamics in …
https://pubmed.ncbi.nlm.nih.gov/31315173/
WEBJul 16, 2019 · Cardiolipin (CL) is a unique phospholipid which is localized and synthesized in the inner mitochondrial membrane (IMM). It is now widely accepted that CL plays a central role in many reactions and processes involved …
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Role of Cardiolipin in Mitochondrial Signaling Pathways
https://www.frontiersin.org/articles/10.3389/fcell.2017.00090/full
WEBSep 29, 2017 · The phospholipid cardiolipin (CL) is a hallmark lipid of mitochondria and almost exclusively found in mitochondrial membranes ( Pangborn, 1945 ). CL is predominantly located in the inner membrane and associated to many mitochondrial functions (see below).
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Cardiolipin’s Remodeling Rules Revealed: The Role of the …
https://www.cell.com/cell-reports/fulltext/S2211-1247(20)30316-8
WEBMar 24, 2020 · Cardiolipin is a mitochondria-specific, dimeric phospholipid that localizes primarily to the inner mitochondrial membrane. It is important for a range of mitochondrial functions including maintenance of cristae structure, organization of the respiratory complexes, protein import, and cellular signaling, among others ( Anzmann et al., 2019. ).
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